Bronchogenic Carcinoma Presenting as Carcinomatous Meningitis

Bronchogenic Carcinoma Presenting as Carcinomatous Meningitis

Neoplastic meningitis, also known as carcinomatous meningitis, reflects the metastatic infiltration of the cerebrospinal fluid (CSF) and leptomeninges (pia and arachnoid) by cancer. It is the is the third most common cause of central nervous system (CNS) metastases after brain metastases and epidural spinal cord compression [1]. Leptomeningeal metastasis (LMM) is a devastating complication of m...

Numb chin syndrome as the presenting symptom of carcinomatous meningitis.

The numb chin syndrome (NCS) is a rare neurological condition which origins in the absence of a dental cause and is most often associated with malignancy [1–5]. Patients develop orofacial paraesthesia typically localized to the chin and lower lip. We present a series of four female patients (mean age = 66.2 years) who had been diagnosed with breast cancer and were complaining of orofacial numbn...

Bronchogenic carcinoma presenting as a pseudopregnancy.

A young woman with an occult bronchogenic carcinoma presented with secondary amenorrhea and an elevated beta subunit of human chorionic gonadotropin that was mistakenly attributed to pregnancy. Physicians should be aware that this carcinoma may present solely with an elevated beta human chorionic gonadotropin value, and the potential exists for confusion with a pregnancy state in women of child...

Carcinomatous Meningitis from Unknown Primary Carcinoma

Carcinomatous meningitis (CM) occurs in 3 to 8% of cancer patients. Patients present with a focal symptom, and multifocal signs are often found following neurological examination. The gold standard for diagnosis remains the demonstration of carcinomatous cells in the cerebrospinal fluid on cytopathological examination. Despite the poor prognosis, palliative treatment could improve quality of li...

Spontaneous hemothorax as a presenting form of bronchogenic carcinoma.